Archives of Pediatrics and Adolescent Medicine · 1985 · 35 citations · 24 references
MedicineEndocrinologyPhysiologyDiabetologyExercise PhysiologyPhysical ActivityDiabetes ManagementDiabetes MellitusGlycemic ControlMetabolic Adaptation To ExerciseMetabolic Responses To ExercisePhysical FitnessAtherosclerotic Disease PreventionExercise-induced Insulin SensitivityInsulin Sensitivity AdaptationInsulin Sensitivity After ExercisePsychosocial FunctioningTraining
Physical exercise has long been a cornerstone in the management of diabetes mellitus based on its potential to improve metabolic control and to diminish risk factors for atherosclerotic vascular disease common in older diabetic persons.<sup>1-3</sup>Participation in physical activity may also have psychosocial benefits in improving selfesteem and feelings of well-being, which are especially important in patients with chronic disease.<sup>4</sup> Efforts to document the physiologic responses to exercise in patients with diabetes mellitus have only recently been successful. The recognition that serum glycosylated hemoglobin (HbA<sub>1</sub>) levels provide a valid marker of metabolic control<sup>5,6</sup>and the use of euglycemic clamp techniques in determination of insulin sensitivity<sup>7</sup>have allowed new insights into the diabetesexercise relationship. These studies have indicated differences in type 1 (insulin-dependent) and type 2 (adultonset) diabetic patients and have also separated alterations in metabolic status created by short-term exercise from those resulting from physical
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The Treatment of Diabetes Mellitus
Elliott P. Joslin · New England Journal of Medicine · 1913 · 601 citations · Full text