Journal of Materials Chemistry · 2010 · 438 citations · 107 references
Materials ScienceEngineeringPolymer TechnologySmart PolymerShape Memory PolymersShape Memory BehaviorPolymer ScienceBiomaterials DesignPolymer EngineeringBiofabricationPrimary ShapeBiomedical EngineeringSoft MatterBiophysicsPolymer ChemistryPolymers
Shape memory polymers (SMPs) are smart materials that can remember a primary shape and can return to this primary shape from a deformed secondary shape when given an appropriate stimulus. This property allows them to be delivered in a compact form via minimally invasive surgeries in humans, and deployed to achieve complex final shapes. Here we review the various biomedical applications of SMPs and the challenges they face with respect to actuation and biocompatibility. While shape memory behavior has been demonstrated with heat, light and chemical environment, here we focus our discussion on thermally stimulated SMPs.
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Multilineage Potential of Adult Human Mesenchymal Stem Cells
Mark F. Pittenger, Alastair M. Mackay, Stephen C. Beck et al. · Science · 1999 · 20.9K citations
Adult Stem Cell, Multilineage Potential, Biomedical Engineering +16