Concepedia

NIK Controls Classical and Alternative NF-κB Activation and Is Necessary for the Survival of Human T-cell Lymphoma Cells

Lina Odqvist, Margarita Sánchez‐Beato, Santiago Montes‐Moreno, Esperanza Martín‐Sánchez, Raquel Pajares, Lydia Sánchez-Verde, Pablo L. Ortiz‐Romero, José Rodríguez, Socorro Marıá Rodríguez-Pinilla, F. Martínez,

Clinical Cancer Research · 2013 · 56 citations · 38 references

DOI

Abstract

The results of the present study indicate that NIK could be a promising therapeutic target in these aggressive malignancies.

References

38

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

Ash A. Alizadeh, Michael B. Eisen, R. Eric Davis et al. · Nature · 2000 · 9.9K citations

, , +8

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

Sergei I. Grivennikov, Eliad Karin, Janoš Terzić et al. · Cancer Cell · 2009 · 2.1K citations · Full text

, , +10

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

R. Eric Davis, Vu N. Ngo, Georg Lenz et al. · Nature · 2010 · 1.6K citations · Full text

, , +4

Activation of interleukin-6 gene expression through the NF-kappa B transcription factor.

Towia A. Libermann, David Baltimore · Molecular and Cellular Biology · 1990 · 1.4K citations

, , +17

Activation by IKKα of a Second, Evolutionary Conserved, NF-κB Signaling Pathway

Uwe Senftleben, Yixue Cao, Gutian Xiao et al. · Science · 2001 · 1.3K citations

, , +21