Lack of tolerance to the anxiolytic effect of diazepam and pentobarbital following chronic administration in perinatally undernourished rats

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

Sharon Pellow, Philippe Chopin, Sandra E. File et al. · Journal of Neuroscience Methods · 1985 · 5.8K citations

Social Sciences, Behavioral Sciences, Psychology +9

Functional Coupling of γ-Aminobutyric Acid Receptors to Chloride Channels in Brain Membranes

R. Adron Harris, Andrea M. Allan · Science · 1985 · 272 citations

Life Sciences, Neuroscience, Pharmacology +17

Chronic benzodiazepine administration. I. Tolerance is associated with benzodiazepine receptor downregulation and decreased gamma-aminobutyric acidA receptor function.

Lawrence G. Miller, D J Greenblatt, Jamie Barnhill et al. · Journal of Pharmacology and Experimental Therapeutics · 1988 · 219 citations

Medicine, Pharmacokinetics, Pharmacology +13

Chronic ethanol and pentobarbital administration in the rat: Effects on GABAA receptor function and expression in brain

A. Leslie Morrow, Pascale Montpied, Anne Lingford‐Hughes et al. · Alcohol · 1990 · 142 citations

Medicine, Neuroscience, Pharmacology +11

Effects of continuous diazepam administration on GABAA subunit mRNA in rat brain

Catharine Heninger, Naoaki Saito, John F. Tallman et al. · Journal of Molecular Neuroscience · 1990 · 119 citations

Life Sciences, Neuroscience, Pharmacology +15