Concepedia

p53 and MDM2 immunostaining in pulmonary blastomas and bronchogenic carcinomas

Susan Pacinda, S. C. Ledet, Margaret Gondo, Claire Langston, Richard W. Brown, Pedro A. Carmona, Raymond B. Franklin, Victor L. Roggli, Philip T. Cagle

Human Pathology · 1996 · 27 citations · 25 references

DOI

Concepts

References

25

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

Jamil Momand, Gerard P. Zambetti, David C. Olson et al. · Cell · 1992 · 3.1K citations

, , +10

mdm2 expression is induced by wild type p53 activity.

Yaacov Barak, T. Juven, Rebecca Haffner et al. · The EMBO Journal · 1993 · 1.3K citations · Full text

, , +8

Increased expression of mutant forms of p53 oncogene in primary lung cancer

Richard Iggo, Jiří Bártek, David P. Lane et al. · The Lancet · 1990 · 1K citations

, , +16

p53 Mutation and MDM2 amplification in human soft tissue sarcomas.

Fredrick S. Leach, Takashi Tokino, Paul S. Meltzer et al. · PubMed · 1993 · 538 citations

, , +15

Aberrant expression of the p53 oncoprotein is a common feature of a wide spectrum of human malignancies.

Jiří Bártek, Jiřina Bártková, Bořivoj Vojtěšek et al. · PubMed · 1991 · 510 citations

, , +13