Tolerance to organic nitrates: Clinical and experimental perspectives

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

L J Ignarro, Howard Lippton, Jo C. W. Edwards et al. · Journal of Pharmacology and Experimental Therapeutics · 1981 · 1.6K citations

Life Sciences, Biophysics, Physiology +6

MECHANISM OF TOLERANCE DEVELOPMENT TO ORGANIC NITRATES

Philip Needleman, Eugene M. Johnson · Journal of Pharmacology and Experimental Therapeutics · 1973 · 499 citations

Life Sciences, Biochemistry, Physiology +10

Oral Isosorbide dinitrate in angina pectoris: Comparison of duration of action and dose-response relation during acute and sustained therapy

Udho Thadani, Ho‐Leung Fung, Andrew C. Darke et al. · The American Journal of Cardiology · 1982 · 300 citations

Medicine, Cardiology, Pharmacology +9

Improved exercise capacity and differing arterial and venous tolerance during chronic isosorbide dinitrate therapy for congestive heart failure.

C V Leier, Patricia Huss, Raymond D. Magorien et al. · Circulation · 1983 · 294 citations

Pharmacy, Cardiology, Pharmacotherapy +15

Nonatheromatous Ischemic Heart Disease following Withdrawal from Chronic Industrial Nitroglycerin Exposure

Ramon L. Lange, Michael S. Reid, Donald D. Tresch et al. · Circulation · 1972 · 263 citations · Full text

Medicine, Cardiology, Internal Medicine +14