Concepedia

Quantification of the anti-leukemia drug STI571 (Gleevec™) and its metabolite (CGP 74588) in monkey plasma using a semi-automated solid phase extraction procedure and liquid chromatography-tandem mass spectrometry

Ray Bakhtiar, Lakshmi Khemani, Michael Hayes, T. Bedman, Francis L. S. Tse

Journal of Pharmaceutical and Biomedical Analysis · 2002 · 73 citations · 32 references

DOI

Concepts

References

32

Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia

Brian Druker, Moshe Talpaz, Debra Resta et al. · New England Journal of Medicine · 2001 · 5.2K citations · Full text

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Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia with the Philadelphia Chromosome

Brian Druker, Charles L. Sawyers, Hagop M. Kantarjian et al. · New England Journal of Medicine · 2001 · 2.7K citations · Full text

, , +17

Effect of the Tyrosine Kinase Inhibitor STI571 in a Patient with a Metastatic Gastrointestinal Stromal Tumor

Heikki Joensuu, Peter Roberts‎, Maarit Sarlomo‐Rikala et al. · New England Journal of Medicine · 2001 · 2.1K citations · Full text

, , +17

Structural Mechanism for STI-571 Inhibition of Abelson Tyrosine Kinase

Thomas H. Schindler, William G. Bornmann, Patricia Pellicena et al. · Science · 2000 · 1.8K citations

, , +16

The molecular biology of chronic myeloid leukemia

Michael W. Deininger, John M. Goldman, Junia V. Melo · Blood · 2000 · 1.6K citations

, , +14