Role of the acyl groups in carbohydrate chains in cytotoxic properties of olivomycin A

Novel GC-rich DNA-binding compound produced by a genetically engineered mutant of the mithramycin producer Streptomyces argillaceus exhibits improved transcriptional repressor activity: implications for cancer therapy

Veronica Albertini · Nucleic Acids Research · 2006 · 93 citations · Full text

Medicine, Cancer Biology, Oncology +14

Crystal structure of the [Mg2+-(chromomycin A3)2]-d(TTGGCCAA)2 complex reveals GGCC binding specificity of the drug dimer chelated by a metal ion

Ming‐Hon Hou · Nucleic Acids Research · 2004 · 85 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17

Inhibition of c-<i>src</i>Transcription by Mithramycin:  Structure−Activity Relationships of Biosynthetically Produced Mithramycin Analogues Using the c-<i>src</i>Promoter as Target

Lily L. Remsing, Hamid R. Bahadori, Giuseppina M. Carbone et al. · Biochemistry · 2003 · 76 citations

Medicine, Oncology, Pharmacology +14

Role of Magnesium Ion in Mithramycin-DNA Interaction: Binding of Mithramycin-Mg2+ Complexes with DNA

Palok Aich, Dipak Dasgupta · Biochemistry · 1995 · 68 citations

Natural Sciences, Biophysics, Molecular Biology +17

Role of magnesium ion in the interaction between chromomycin A3 and DNA: binding of chromomycin A3-magnesium(2+) complexes with DNA

Palok Aich, Ranjan Sen, Dipak Dasgupta · Biochemistry · 1992 · 64 citations

Natural Sciences, Biophysics, Molecular Biology +17