Concepedia

Antitumor activity of a derivative of mitomycin, 7-N-[2-[[2-(?-l-glutamylamino)ethyl]dithio]ethyl]mitomycin C (KW-2149), against murine and human tumors and a mitomycin C-resistant tumor in vitro and in vivo

Takashi Tsuruo, Yojiro Sudo, N Asami, Makoto Inaba, Makoto Morimoto

Cancer Chemotherapy and Pharmacology · 1990 · 16 citations · 12 references

DOI

Concepts

References

12

Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil.

Takashi Tsuruo, Harumi Iida, Shigeru Tsukagoshi et al. · PubMed · 1981 · 1.5K citations

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Isolation and Structure of a Covalent Cross-Link Adduct Between Mitomycin C and DNA

Maria Tomasz, Roselyn Lipman, Dondapati Chowdary et al. · Science · 1987 · 455 citations

, , +15

MX2, a morpholino anthracycline, as a new antitumor agent against drug-sensitive and multidrug-resistant human and murine tumor cells.

Masahiko Watanabe, N Komeshima, S. NAKAJIMA et al. · PubMed · 1988 · 50 citations

, , +10

Synthesis and antitumor activity of a novel water soluble mitomycin analog; 7-N-(2-((2-(.GAMMA.-L-Glutamylamino)ethyl)dithio)ethyl)mitomycin C.

Motomichi Kono, Yutaka Saitoh, Masaji Kasai et al. · Chemical and Pharmaceutical Bulletin · 1989 · 44 citations · Full text

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Responsiveness of human lung cancer/nude mouse to antitumor agents in a model using clinically equivalent doses

Tazuko Tashiro, Makoto Inaba, Tomowo Kobayashi et al. · Cancer Chemotherapy and Pharmacology · 1989 · 42 citations

, , +5