Non-Sonogashira-Type Palladium-Catalyzed Coupling Reactions of Terminal Alkynes Assisted by Silver(I) Oxide or Tetrabutylammonium Fluoride

Abstract

Palladium-catalyzed reaction of aryl and alkenyl halides with terminal alkynes in the presence of silver(I) oxide as an activator furnishes various arylated or alkenylated alkynes in good to excellent yields. The similar coupling reaction is also found to proceed using tetrabutylammonium fluoride (TBAF) or tetrabutylammonium hydroxide (TBAOH) as an activator.