Concepedia

Regio‐ and Enantioselective Iridium‐Catalyzed Allylic Alkylation with In Situ Activated P,C‐Chelate Complexes

Gunter Lipowsky, Nicole Miller, Günter Helmchen

Angewandte Chemie International Edition · 2004 · 150 citations · 18 references

DOI

Concepts

Abstract

Come together: Successful cooperation of iridium and copper yielded a new catalyst system for allylic alkylation. Branched alkylation products can be obtained rapidly and with high enantioselectivity from simple linear precursors (see scheme; cod=cyclooctadiene).

References

18

Readily Available [2.2.2]-Bicyclooctadienes as New Chiral Ligands for Ir(I):  Catalytic, Kinetic Resolution of Allyl Carbonates

Christian Fischer, Christian Defieber, Takeyuki Suzuki et al. · Journal of the American Chemical Society · 2004 · 438 citations

, , +10

Regio- and Enantioselective Allylic Amination of Achiral Allylic Esters Catalyzed by an Iridium−Phosphoramidite Complex

Toshimichi Ohmura, John F. Hartwig · Journal of the American Chemical Society · 2002 · 371 citations

, , +13

A Highly Effective Phosphoramidite Ligand for Asymmetric Allylic Substitution

Karine Tissot‐Croset, Damien Polet, Alexandre Alexakis · Angewandte Chemie International Edition · 2004 · 317 citations · Full text

, , +6

Highly Regio- and Enantioselective Pd-Catalyzed Allylic Alkylation and Amination of Monosubstituted Allylic Acetates with Novel Ferrocene <i>P,N</i>-Ligands

Shu‐Li You, Xia‐Zhen Zhu, Yumei Luo et al. · Journal of the American Chemical Society · 2001 · 311 citations

, , +6

Identification of an Activated Catalyst in the Iridium-Catalyzed Allylic Amination and Etherification. Increased Rates, Scope, and Selectivity

Christoph Kiener, Chutian Shu, Christopher D. Incarvito et al. · Journal of the American Chemical Society · 2003 · 292 citations

, , +16