Trypanocidal activities of trileucine methyl vinyl sulfone proteasome inhibitors

Proteasome inhibitors: a novel class of potent and effective antitumor agents.

Julian Adams, Vito J. Palombella, Edward A. Sausville et al. · PubMed · 1999 · 1.5K citations

Medicine, Oncology, Pharmacology +14

Cultivation in a semi‐defined medium of animal infective forms of Trypanosoma brucei, T. equiperdum, T. evansi, T. rhodesiense and T. gambiense.

T. Baltz, D. Baltz, C. Giroud et al. · The EMBO Journal · 1985 · 564 citations · Full text

Veterinary Medicine, Infectious Diseases, Microbiology +12

Vinyl Sulfones as Mechanism-Based Cysteine Protease Inhibitors

James T. Palmer, David Rasnick, Jeffrey L. Klaus et al. · Journal of Medicinal Chemistry · 1995 · 506 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +6

A comparison of three methods of estimating EC50 in studies of drug resistance of malaria parasites

Werner Huber, Jacob C. Koella · Acta Tropica · 1993 · 481 citations

Medicine, Infectious Diseases, Pharmacology +12

Covalent modification of the active site threonine of proteasomal β subunits and the <i>Escherichia coli</i> homolog HslV by a new class of inhibitors

Matthew Bogyo, John S. McMaster, Maria Gaczyńska et al. · Proceedings of the National Academy of Sciences · 1997 · 444 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16