GPR30 and estrogen receptor expression: new insights into hormone dependence of inflammatory breast cancer

A Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling

Chetana M. Revankar, Daniel F. Cimino, Larry A. Sklar et al. · Science · 2005 · 2.3K citations

Life Sciences, Biochemistry, Cell Biology +10

Identity of an Estrogen Membrane Receptor Coupled to a G Protein in Human Breast Cancer Cells

Peter Thomas, Yefei Pang, Edward J. Filardo et al. · Endocrinology · 2004 · 1.4K citations · Full text

Life Sciences, Endocrinology, Molecular Biology +17

Estrogen-Induced Activation of Erk-1 and Erk-2 Requires the G Protein-Coupled Receptor Homolog, GPR30, and Occurs via Trans-Activation of the Epidermal Growth Factor Receptor through Release of HB-EGF

Edward J. Filardo, Jeffrey A. Quinn, Kirby I. Bland et al. · Molecular Endocrinology · 2000 · 1.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Estrogen Action Via the G Protein-Coupled Receptor, GPR30: Stimulation of Adenylyl Cyclase and cAMP-Mediated Attenuation of the Epidermal Growth Factor Receptor-to-MAPK Signaling Axis

Edward J. Filardo, Jeffrey A. Quinn, A. Raymond Frackelton et al. · Molecular Endocrinology · 2002 · 854 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Virtual and biomolecular screening converge on a selective agonist for GPR30

Cristian Bologa, Chetana M. Revankar, Susan Young et al. · Nature Chemical Biology · 2006 · 814 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12