Concepedia

Rationale for Fixed Dosing of Pertuzumab in Cancer Patients Based on Population Pharmacokinetic Analysis

Chee M. Ng, Bert L. Lum, Verónica C. Giménez, Steve Kelsey, David Allison

Pharmaceutical Research · 2006 · 99 citations · 13 references

DOI

Concepts

References

13

Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab

Hyun‐Soo Cho, Karen Mason, Kasra X. Ramyar et al. · Nature · 2003 · 1.6K citations

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Evaluating Pharmacokinetic/Pharmacodynamic Models Using the Posterior Predictive Check

Yoshitaka Yano, Stuart L. Beal, Lewis B. Sheiner · Journal of Pharmacokinetics and Pharmacodynamics · 2001 · 402 citations

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Phase I Clinical Study of Pertuzumab, a Novel HER Dimerization Inhibitor, in Patients With Advanced Cancer

David B. Agus, Michael S. Gordon, Charles Taylor et al. · Journal of Clinical Oncology · 2005 · 388 citations · Full text

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Pharmacokinetics, Safety, and Efficacy of Trastuzumab Administered Every Three Weeks in Combination With Paclitaxel

Brian Leyland‐Jones, Karen A. Gelmon, Jean-Pierre Ayoub et al. · Journal of Clinical Oncology · 2003 · 296 citations

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Assessment of Actual Significance Levels for Covariate Effects in NONMEM

Ulrika Wählby, E. Niclas Jonsson, Mats O. Karlsson · Journal of Pharmacokinetics and Pharmacodynamics · 2001 · 286 citations

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