Concepedia

Pharmacological reduction of ER stress protects against TDP-43 neuronal toxicity in vivo

Alexandra Vaccaro, Shunmoogum A. Patten, Dina Aggad, Carl Julien, Claudia Maios, Edor Kabashi, Pierre Drapeau, J. Alex Parker

Neurobiology of Disease · 2013 · 135 citations · 33 references

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33

Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis

Manuela Neumann, Deepak M. Sampathu, Linda K. Kwong et al. · Science · 2006 · 6.6K citations

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A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD

Alan E. Renton, Elisa Majounie, Adrian J. Waite et al. · Neuron · 2011 · 4.5K citations · Full text

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An Integrated Stress Response Regulates Amino Acid Metabolism and Resistance to Oxidative Stress

Heather P. Harding, Yuhong Zhang, Huiquing Zeng et al. · Molecular Cell · 2003 · 3.3K citations · Full text

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IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

Marcella A. Calfon, Huiqing Zeng, Fumihiko Urano et al. · Nature · 2002 · 2.9K citations

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Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

Caroline Vance, Boris Rogelj, Tibor Hortobágyi et al. · Science · 2009 · 2.6K citations · Full text

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