Lipophilic Di‐ and Triamides as Ionophores for Alkaline Earth Metal Cations

Daniel Erne, Nada Stojanac, Daniel Ammann, Peter Hofstetter, Ernö Pretsch, W. Simon

Helvetica Chimica Acta · 1980 · 48 citations · 14 references

Concepts

Abstract

Abstract Different electrically neutral lipophilic di‐ and triamides were prepared and their ion selectivity in membranes studied. In membranes the ionophore N , N′ ‐diheptyl‐ N , N′ ‐dimethyl‐succinamide prefers Ca 2+ over Mg 2+ by a factor of 20 but rejects Na + and K + in respect to Mg 2+ by a factor of 100 and 10, respectively. This selectivity suffices to perform useful intracellular Mg 2+ activity studies.

References

14