E12 and E47 modulate cellular localization and proteasome-mediated degradation of MyoD and Id1

The protein Id: A negative regulator of helix-loop-helix DNA binding proteins

Robert Benezra, Robert L. Davis, Daniel Lockshon et al. · Cell · 1990 · 2.3K citations

Negative Regulator, Molecular Research, Natural Sciences +7

Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1

Kiichiro Tomoda, Yukiko Kubota, Jun‐ya Kato · Nature · 1999 · 640 citations

Signal Transduction, Signaling Pathway, Biochemistry +11

Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins.

Xiaohong Sun, Neal G. Copeland, Nancy A. Jenkins et al. · Molecular and Cellular Biology · 1991 · 590 citations

Genetics, Genomic Mechanism, Molecular Biology +17

Degradation of MyoD Mediated by the SCF (MAFbx) Ubiquitin Ligase

Lionel Tintignac, Julie Lagirand, Sabrina Batonnet et al. · Journal of Biological Chemistry · 2004 · 392 citations · Full text

Protein Function, Biochemistry, Ubiquitin-proteasome Pathway +15

A novel site for ubiquitination: the N-terminal residue, and not internal lysines of MyoD, is essential for conjugation and degradation of the protein

Kristin Breitschopf · The EMBO Journal · 1998 · 283 citations · Full text

Protein Chemistry, Protein Function, Biochemistry +11