Angewandte Chemie International Edition · 2008 · 69 citations · 14 references
Natural SciencesChemistryPharmaceuticsDrug DeliveryNanoparticle Drug DeliveryPolymer ChemistryDrug EncapsulationNanocarriers For TherapeuticsNanomaterials For Drug DeliveryNanomedicineNanoparticle SynthesisSupramolecular PolymersCyclodextrin-based NanocarriersDrug-loaded MicellesMicelle Drug DeliveryMicellesNanoparticlesPolymer MicellesPolymeric MicellesPolymeric Nanoparticle Synthesis
A matter of control: A method has been developed for the construction of supramolecular polymer micelles (SMPMs) from α-cyclodextrin (α-CD) and poly(ε-caprolactone) (PCL) by controlling the intermolecular hydrogen bonds between CDs (see scheme). These micelles show great potential for use as drug carriers, templates for the synthesis of inorganic nanoparticles, and nanoreactors.
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