Boophilus microplus: Its saliva contains microphilin, a small thrombin inhibitor

Design and characterization of hirulogs: a novel class of bivalent peptide inhibitors of thrombin

John M. Maraganore, P Bourdon, Jo-Ann Jablonski et al. · Biochemistry · 1990 · 468 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Tick Anticoagulant Peptide (TAP) Is a Novel Inhibitor of Blood Coagulation Factor Xa

Lloyd Waxman, Donna Smith, Karen E. Arcuri · Science · 1990 · 415 citations

Medicine, Immunology, Pharmacology +13

Refined structure of the Hirudin-thrombin complex

T.J. Rydel, A. Tulinsky, Wolfram Bode et al. · Journal of Molecular Biology · 1991 · 373 citations

Life Sciences, Biochemistry, Molecular Biology +10

Ixolaris, a novel recombinant tissue factor pathway inhibitor (TFPI) from the salivary gland of the tick, Ixodes scapularis: identification of factor X and factor Xa as scaffolds for the inhibition of factor VIIa/tissue factor complex

Ivo M.B. Francischetti, Jesús G. Valenzuela, John F. Andersen et al. · Blood · 2002 · 264 citations · Full text

Life Sciences, Immunology, Gene Expression +10

A Kazal-type inhibitor with thrombin specificity from Rhodnius prolixus

Thomas Friedrich, Burkhard Kröger, Siegfried Bialojan et al. · Journal of Biological Chemistry · 1993 · 190 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17