Protective effects of hydrogen-rich saline in a rat model of permanent focal cerebral ischemia via reducing oxidative stress and inflammatory cytokines

Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals

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Life Sciences, Biochemistry, Pharmacology +13

Neurological Deficit and Extent of Neuronal Necrosis Attributable to Middle Cerebral Artery Occlusion in Rats

Julio Herrero García, Simone Wagner, Kai-Feng Liu et al. · Stroke · 1995 · 1.5K citations

Medicine, Neuroscience, Surgery +14

Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia–reperfusion injury

Kentaro Hayashida, Motoaki Sano, Ikuroh Ohsawa et al. · Biochemical and Biophysical Research Communications · 2008 · 475 citations

Medicine, Cardiology, Physiology +6

Inhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress

Kei-ichi Fukuda, Sadamitsu Asoh, Masahiro Ishikawa et al. · Biochemical and Biophysical Research Communications · 2007 · 410 citations

Pharmacy, Biochemistry, Toxicology +16

Anti-high Mobility Group Box-1 Monoclonal Antibody Protects the Blood–Brain Barrier From Ischemia-Induced Disruption in Rats

Jiyong Zhang, Hideo Takahashi, Keyue Liu et al. · Stroke · 2011 · 316 citations

Medicine, Neurobiology, Neuroscience +17