Neurologic Disorders Due to Brain Manganese Deposition in a Jaundiced Patient Receiving Long‐Term Parenteral Nutrition

Abstract

Our observation is the first demonstration of a relationship between high intracerebral manganese levels, radiologic abnormalities, and neurologic disorders during long-term PN. Moreover, serum manganese levels are not a good indicator of cerebral levels. In fact, in our patient, serum manganese levels returned to normal, whereas those of cerebral manganese remained increased.