Concepedia

High Performance Liquid Chromatography–Mass Spectrometry Assay for Polymyxin B1 and B2 in Human Plasma

Tiffany Thomas, Emily C. Broun, Kirsten Abildskov, Christine J. Kubin, Jennifer Horan, Michael T. Yin, Serge Cremers

Therapeutic Drug Monitoring · 2012 · 47 citations · 14 references

DOIFull text

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Abstract

A simple method for the simultaneous measurement of polymyxin B1 and polymyxin B2 in human plasma is described, which has the potential to optimize clinical use of this valuable antibiotic by permitting pharmacokinetic studies and therapeutic drug monitoring.

References

14

Colistin-resistant isolates of Klebsiella pneumoniae emerging in intensive care unit patients: first report of a multiclonal cluster

Anastasia Antoniadou, Flora Kontopidou, G. Poulakou et al. · Journal of Antimicrobial Chemotherapy · 2007 · 270 citations

Pharmacokinetics of Intravenous Polymyxin B in Critically Ill Patients

Alexandre Prehn Zavascki, Luciano Zubaran Goldani, Guoying Cao et al. · Clinical Infectious Diseases · 2008 · 232 citations · Full text

, , +21

In Vitro Pharmacodynamic Properties of Colistin and Colistin Methanesulfonate against <i>Pseudomonas aeruginosa</i> Isolates from Patients with Cystic Fibrosis

Jian Li, John Turnidge, Robert Milne et al. · Antimicrobial Agents and Chemotherapy · 2001 · 226 citations · Full text

, , +13

Pharmacodynamics of Polymyxin B against <i>Pseudomonas aeruginosa</i>

Vincent H. Tam, Amy N. Schilling, Giao Vo et al. · Antimicrobial Agents and Chemotherapy · 2005 · 204 citations · Full text

, , +15

Assay of Colistin and Colistin Methanesulfonate in Plasma and Urine by Liquid Chromatography-Tandem Mass Spectrometry

Patrice Gobin, Sandrine Marchand, William Couet et al. · Antimicrobial Agents and Chemotherapy · 2010 · 147 citations · Full text

, , +17