Comparison of Intrapulmonary and Systemic Pharmacokinetics of Colistin Methanesulfonate (CMS) and Colistin after Aerosol Delivery and Intravenous Administration of CMS in Critically Ill Patients

Matthieu Boisson, Matthieu Jacobs, Nicolas Grégoire, +4

Antimicrobial Agents and Chemotherapy

Gastrointestinal PharmacologyGastroenterologySystemic PharmacokineticsAntimicrobial ChemotherapyColistin Methanesulfonate +16

Assay of Colistin and Colistin Methanesulfonate in Plasma and Urine by Liquid Chromatography-Tandem Mass Spectrometry

Patrice Gobin, Sandrine Marchand, William Couet, +1

Antimicrobial Agents and Chemotherapy

Cms ConcentrationsEngineeringGastrointestinal PharmacologyColistin MethanesulfonateGas Chromatography +15

Passive and active strategies for transdermal delivery using co-encapsulating nanostructured lipid carriers: In vitro vs. in vivo studies

Carla Vitorino, António J. Almeida, João Sousa, +6

European Journal of Pharmaceutics and Biopharmaceutics

NanoparticlesNanomedicineTransdermal DeliveryEngineeringVitro Vs. +6

Aerosol Therapy with Colistin Methanesulfonate: a Biopharmaceutical Issue Illustrated in Rats

Sandrine Marchand, Patrice Gobin, Julien Brillault, +5

Antimicrobial Agents and Chemotherapy

Biopharmaceutical IssueCms ConcentrationsGastrointestinal PharmacologyGastroenterologyPathology +15

Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 3. Tobramycin

Sandrine Marchand, Nicolas Grégoire, Julien Brillault, +3

Antimicrobial Agents and Chemotherapy

Antibacterial AgentsAntimicrobial ChemotherapyPharmacodynamic ModelingBioanalysisBiopharmaceutical Characterization +23

Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 2. Colistin

Aline Vidal Lacerda Gontijo, Nicolas Grégoire, Isabelle Lamarche, +3

Antimicrobial Agents and Chemotherapy

Pharmacokinetics of nebulized colistin methanesulfonate in critically ill patients

Matthieu Boisson, Nicolas Grégoire, Marielle Cormier, +4

Journal of Antimicrobial Chemotherapy

Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 1. Ciprofloxacin, Moxifloxacin, and Grepafloxacin

Aline Vidal Lacerda Gontijo, Julien Brillault, Nicolas Grégoire, +4

Antimicrobial Agents and Chemotherapy

Antibacterial AgentsLocal PharmacologyAntimicrobial ChemotherapyPharmacodynamic ModelingDrug Resistance +27

Pulmonary pharmacokinetics of levofloxacin in rats after aerosolization of immediate-release chitosan or sustained-release PLGA microspheres

Marisa C. Gaspar, Nicolas Grégoire, João Sousa, +6

European Journal of Pharmaceutical Sciences

Lung DepositionPharmacologyPulmonary PharmacologyImmediate-release ChitosanDrug Delivery System +3

Convulsions and apnoea in a patient infected with New Delhi metallo-β-lactamase-1 Escherichia coli treated with colistin

Herbert Spapen, Patrick M. Honoré, Nicolas Grégoire, +5

Journal of Infection

Klebsiella PneumoniaeMicrobiologyInfection ControlMedicineClinical Microbiology +1