Altered Expression of Succinic Dehydrogenase in Asthenozoospermia Infertile Male

Abstract

Dispersed expression of mitochondrial SDH in head and mid-piece of spermatozoa of asthenozoospermia subjects indicates mitochondrial damage because of metabolic or genetic factors, affecting energy production and leading to disturbed sperm motility, which could be pathologically significant. Detailed mitochondrial SDH immunolocalization studies are warranted to establish a role of deranged tricarboxylic acid cycle in causation of male infertility.