Mitochondria-related male infertility

Kazuto Nakada, Akitsugu Sato, Kayo Yoshida, +5

Proceedings of the National Academy of Sciences

SpermatogenesisFertilityMutant MtdnaGeneticsMolecular Genetics +27

Gene therapy for progeny of mito-mice carrying pathogenic mtDNA by nuclear transplantation

Akitsugu Sato, Tomohiro Kono, Kazuto Nakada, +4

Proceedings of the National Academy of Sciences

Selective and Continuous Elimination of Mitochondria Microinjected Into Mouse Eggs From Spermatids, but Not From Liver Cells, Occurs Throughout Embryogenesis

Hiroshi Shitara, Hideki Kaneda, Akitsugu Sato, +4

Genetics

Generation of trans-mitochondrial mice carrying homoplasmic mtDNAs with a missense mutation in a structural gene using ES cells

Atsuko Kasahara, Kaori Ishikawa, Makiko Yamaoka, +9

Human Molecular Genetics

Rare creation of recombinant mtDNA haplotypes in mammalian tissues

Akitsugu Sato, Kazuto Nakada, Miho Akimoto, +5

Proceedings of the National Academy of Sciences

Genome InstabilityHaplotype DeterminationDnaRare CreationNatural Sciences +13

Non‐invasive visualization of sperm mitochondria behavior in transgenic mice with introduced green fluorescent protein (GFP)

Hiroshi Shitara, Hideki Kaneda, Akitsugu Sato, +4

FEBS Letters

SpermatogenesisSperm Mitochondrial DnaGeneticsMolecular BiologyMolecular Genetics +15

Deletion-Mutant mtDNA Increases in Somatic Tissues but Decreases in Female Germ Cells With Age

Akitsugu Sato, Kazuto Nakada, Hiroshi Shitara, +3

Genetics

Normal mitochondrial respiratory function is essential for spatial remote memory in mice

Daisuke Tanaka, Kazuto Nakada, Keizo Takao, +6

Molecular Brain

Over-expression of Tfam improves the mitochondrial disease phenotypes in a mouse model system

Satoshi Nishiyama, Hiroshi Shitara, Kazuto Nakada, +7

Biochemical and Biophysical Research Communications

MitophagyMitochondrial BiogenesisMitochondrial FunctionMouse Model SystemMitochondrial Disease Phenotypes +6

Accumulation of pathogenic ΔmtDNA induced deafness but not diabetic phenotypes in mito-mice

Kazuto Nakada, Akitsugu Sato, Atsuko Kasahara, +4

Biochemical and Biophysical Research Communications

Knockout MouseMolecular PhysiologyDisease MechanismMitochondrial FunctionDiabetic Phenotypes +6