Immunization with a LEAPS™ heteroconjugate containing a CTL epitope and a peptide from beta-2-microglobulin elicits a protective and DTH response to herpes simplex virus type 1

The three-dimensional structure of HLA-B27 at 2.1 Å resolution suggests a general mechanism for tight peptide binding to MHC

Dean R. Madden, Joan C. Gorga, J L Strominger et al. · Cell · 1992 · 663 citations

Life Sciences, Immunology, Molecular Biology +16

Costimulation of proliferative responses of resting CD4+ T cells by the interaction of VLA-4 and VLA-5 with fibronectin or VLA-6 with laminin.

Yoji Shimizu, G A van Seventer, Kevin Horgan et al. · The Journal of Immunology · 1990 · 396 citations

Life Sciences, Cell Biology, Immunology +13

MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8

Rolf König, Li-Yun Huang, Ronald N. Germain · Nature · 1992 · 365 citations

Life Sciences, Immunology, Molecular Biology +14

Identification of a CD4 binding site on the β2 domain of HLA-DR molecules

Giancarlo Cammarota, Armella Scheirle, Béla Takács et al. · Nature · 1992 · 267 citations

Life Sciences, Immunology, Molecular Biology +13

CD8Tc1 and Tc2 cells secrete distinct cytokine patterns in vitro and in vivo but induce similar inflammatory reactions

L Li, Subash Sad, David Kägi et al. · The Journal of Immunology · 1997 · 120 citations

Life Sciences, Immunology, Pathology +17