A six-nucleotide insertion-deletion polymorphism in the CASP8 promoter is associated with susceptibility to multiple cancers

FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex

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Death-inducing Signaling Complex, Signal Transduction, Signaling Pathway +11

Involvement of MACH, a Novel MORT1/FADD-Interacting Protease, in Fas/APO-1- and TNF Receptor–Induced Cell Death

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Inflammation, Novel Mort1/fadd-interacting Protease, Protein Function +10

Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation

S T Ju, D J Panka, Haili Cui et al. · Nature · 1995 · 1.5K citations

Signal Transduction, Lymphocyte Development, T-regulatory Cell +11

A Single Nucleotide Polymorphism in the MDM2 Promoter Attenuates the p53 Tumor Suppressor Pathway and Accelerates Tumor Formation in Humans

Gareth L. Bond, Wenwei Hu, Elisabeth E. Bond et al. · Cell · 2004 · 1.3K citations · Full text

Mdm2 Promoter, Single Nucleotide Polymorphism, Oncogenic Agent +10

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)

Jan Paul Medema · The EMBO Journal · 1997 · 1.2K citations · Full text

Signal Transduction, Pathogenesis, Immunology +6