Concepedia

Discovery of novel, orally available benzimidazoles as melanin concentrating hormone receptor 1 (MCHR1) antagonists

Pradip K. Sasmal, Sanjita Sasmal, P. Tirumala Rao, B. Venkatesham, M. Roshaiah, Chandrasekhar Abbineni, Ish Khanna, Vikram P. Jadhav, J. Suresh, Rashmi Talwar,

Bioorganic & Medicinal Chemistry Letters · 2010 · 14 citations · 33 references

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33

A role for melanin-concentrating hormone in the central regulation of feeding behaviour

Daqing Qu, David S. Ludwig, Steen Gammeltoft et al. · Nature · 1996 · 1.3K citations

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Mice lacking melanin-concentrating hormone are hypophagic and lean

Masako Shimada, Nicholas A. Tritos, Bradford B. Lowell et al. · Nature · 1998 · 1.2K citations

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Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance

David S. Ludwig, Nicholas A. Tritos, Jason Mastaitis et al. · Journal of Clinical Investigation · 2001 · 624 citations · Full text

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Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism

Donald J. Marsh, Drew T. Weingarth, Dawn E. Novi et al. · Proceedings of the National Academy of Sciences · 2002 · 551 citations

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Hypothalamic Pro-Opiomelanocortin mRNA Is Reduced By Fasting in <i>ob/ob</i> and <i>db/db</i> Mice, but Is Stimulated by Leptin

Tooru M. Mizuno, Steven P. Kleopoulos, Hugo Bergen et al. · Diabetes · 1998 · 525 citations · Full text

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