Apoptotic Cell Death and Impairment of L-Type Voltage-Sensitive Calcium Channel Activity in Rat Cerebellar Granule Cells Treated with the Prion Protein Fragment 106–126

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

Natural Sciences, Biochemistry, Chemistry +17

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins.

K M Pan, M. A. Baldwin, Jack Nguyen et al. · Proceedings of the National Academy of Sciences · 1993 · 2.3K citations

Life Sciences, Biochemistry, Molecular Biology +17

NMR solution structure of the human prion protein

Ralph Zahn, Aizhuo Liu, Thorsten Lührs et al. · Proceedings of the National Academy of Sciences · 2000 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +16

Neurotoxicity of a prion protein fragment

Gianluigi Forloni, Nadia Angeretti, Roberto Chiesa et al. · Nature · 1993 · 943 citations

Life Sciences, Neurobiology, Neuroscience +12

Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein

Glenn C. Telling, Michael Scott, James A. Mastrianni et al. · Cell · 1995 · 850 citations · Full text

Veterinary Medicine, Genetics, Molecular Biology +14