Characterization of furoxans as a new class of tolerance-resistant nitrovasodilators

Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle

Victoria M. Bolotina, Soheil Najibi, James Palacino et al. · Nature · 1994 · 1.7K citations

Natural Sciences, Biophysics, Physiology +12

Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta.

William Martin, G. Villani, D Jothianandan et al. · Journal of Pharmacology and Experimental Therapeutics · 1985 · 1.3K citations

Medicine, Pharmacology, Physiology +8

Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase.

Stephen L. Archer, Jiehuan Huang, Václav Hampl et al. · Proceedings of the National Academy of Sciences · 1994 · 820 citations · Full text

Life Sciences, Pharmacology, Physiology +16

Thiol-mediated generation of nitric oxide accounts for the vasodilator action of furoxans

Martin Feelisch, Karl Schönafingeri, Hike Noack · Biochemical Pharmacology · 1992 · 161 citations

Life Sciences, Biochemistry, Pharmacology +10

Vascular tolerance to nitroglycerin and cyclic GMP generation in rat aortic smooth muscle.

Richard A. Keith, Allan M. Burkman, Theodore D. Sokoloski et al. · Journal of Pharmacology and Experimental Therapeutics · 1982 · 117 citations

Medicine, Pharmacology, Physiology +14