Decreases in anti-double-stranded DNA levels are associated with concurrent flares in patients with systemic lupus erythematosus

Audrey Ho, Laurence S Magder, Susan G. Barr, Michelle Petri

Arthritis & Rheumatism · 2001 · 200 citations · 33 references

Abstract

A previous increase in anti-dsDNA levels occurred before SLE flares, as measured by the M-SLEDAI and M-LAI only. However, during lupus flares, including the subset of renal flares, anti-dsDNA levels frequently decreased. We hypothesize that this decrease in anti-dsDNA represents deposition in tissue at the time of flare.

References

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