Synthetic Communications · 2008 · 20 citations · 21 references
Natural SciencesChemistryMedicinal ChemistryCatalysisCrystal StructureOrganic ChemistryCrystal ChemistryCrystal SystemsHeterocycle SynthesisHeterocyclic ChemistryOrganic SynthesisCrystal Structure RefinementSingle-crystal DiffractionSingle-crystal X-ray DiffractionThiadiazole ChemistryThiazole ChemistryThiazole Synthesis
Abstract An efficient synthesis of some novel 2-aroylimino-3-aryl-4-phenyl-1,3-thiazolines was carried out by base-catalyzed cyclization of 1-aroyl-3-arylthioureas with acetophenone in the presence of bromine. The structures were confirmed by spectroscopic data, elemental analyses, and in one case (2t) by single-crystal X-ray diffraction data.
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