Genistein induces cell apoptosis in MDA-MB-231 breast cancer cells via the mitogen-activated protein kinase pathway

Estrogenic effects of genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo.

Ching‐Yi Hsieh, Ross Santell, Sandra Z. Haslam et al. · PubMed · 1998 · 612 citations

Medicine, Endocrinology, Pharmacology +7

Requirement of NF-κB Activation to Suppress p53-Independent Apoptosis Induced by Oncogenic Ras

Marty W. Mayo, Cun-Yu Wang, Patricia C. Cogswell et al. · Science · 1997 · 535 citations

Medicine, Cancer Biology, Oncology +17

Genistein inhibition of the growth of human breast cancer cells: Independence from estrogen receptors and the multi-drug resistance gene

Gregory W. Peterson, Stephen Barnes · Biochemical and Biophysical Research Communications · 1991 · 468 citations

Medicine, Oncology, Pharmacology +17

Estrogenic and antiproliferative properties of genistein and other flavonoids in human breast cancer cells<i>in vitro</i>

David T. Zava, Gail Duwe · Nutrition and Cancer · 1997 · 465 citations

Medicine, Endocrinology, Oncology +13

Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor

Yutaka Kato, Richard I. Tapping, Shuang Huang et al. · Nature · 1998 · 441 citations

Life Sciences, Cell Biology, Molecular Biology +8