BMJ · 1953 · 18 citations · 2 references
Life SciencesNutritionNutritional SciencesHuman NutritionIron Metabolism DisordersMicronutrient DeficiencyAnemiaIron DeficiencyVitamin B12 DeficiencyVitamin B12 PhysiologyVitamin BiochemistryVitamin PhysiologyPernicious Anemia PhysiologyPretreatmentSerum Micronutrient ConcentrationsVitamin B12 (Cobalamin)Vitamin B12 Deficiency AnemiaVitamin B12 Deficiency TreatmentVitamin B12 Metabolism
The serum vitamin B12 concentrations of patients with pernicious anaemia in relapse rose from low pretreatment levels to within the normal range after single intramuscular injections of 20 to 1,000 ,tg. of vitamin B12. Concentrations were within the normal range for from 6 to more than 18 days after injections of 20 ug.; from 2 to 22 days after 40 ,tg.; from 11 to at least 35 days after 80 jug.; from 11 to at least 48 days after 160 jug.; from 39 to 98 days after-320 ,tg.; and from 34 to at least 58 days after 1,000 ,tg.
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