Concepedia

A Functional Variant in APOA5/A4/C3/A1 Gene Cluster Contributes to Elevated Triglycerides and Severity of CAD by Interfering With MicroRNA 3201 Binding Efficiency

Guanglin Cui, Zongzhe Li, Rui Li, Jin Huang, Haoran Wang, Lina Zhang, Hu Ding, Dao Wen Wang

Journal of the American College of Cardiology · 2014 · 60 citations · 20 references

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Abstract

Genetic variants in APOA5/A4/C3/A1 gene cluster play an important role in the regulation of plasma triglyceride levels by an increased APOA5 concentration and contribute to the severity of CAD.

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