Concepedia

Under‐expression of VHL and over‐expression of HDAC‐1, HIF‐1α, LL‐37, and IAP‐2 in affected skin biopsies of patients with psoriasis

Laura E. Tovar‐Castillo, Juan C. Cancino‐Díaz, Francisco García‐Vázquez, Francisco G. Cancino‐Gómez, Gladys León‐Dorantes, Fernando Blancas‐González, L Jiménez-Zamudio, Ethel García‐Latorre, Mario E. Cancino‐Díaz

International Journal of Dermatology · 2006 · 108 citations · 24 references

DOI

Abstract

These findings suggest that there could be an association of HDAC-1, HIF-1alpha, LL-37, VHL, and IAP-2 with angiogenic and apoptotic mechanisms in psoriasis.

References

24

Endogenous Antimicrobial Peptides and Skin Infections in Atopic Dermatitis

Peck Y. Ong, Takaaki Ohtake, Corinne Brandt et al. · New England Journal of Medicine · 2002 · 1.9K citations · Full text

Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel–Lindau protein

Michael Ohh, Cheol Won Park, Mircea Ivan et al. · Nature Cell Biology · 2000 · 1.6K citations

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Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein.

Othon Iliopoulos, Andrew P. Levy, Cong Jiang et al. · Proceedings of the National Academy of Sciences · 1996 · 893 citations · Full text

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An angiogenic role for the human peptide antibiotic LL-37/hCAP-18

Andreas Rembert Koczulla, Georges von Degenfeld, Christian Kupatt et al. · Journal of Clinical Investigation · 2003 · 833 citations · Full text

The Expression of the Gene Coding for the Antibacterial Peptide LL-37 Is Induced in Human Keratinocytes during Inflammatory Disorders

Margareta Frohm, Birgitta Agerberth, Ghasem Ahangari et al. · Journal of Biological Chemistry · 1997 · 788 citations · Full text