Asymmetric Conjugate Alkenylation of Enones Catalyzed by Chiral Diols

Abstract

Reaction of dimethyl alkenylboronates with α,β-unsaturated ketones in the presence of catalytic amounts of 3,3‘-disubstituted binaphthols provides conjugate alkenylation products in good yields and with generally high (∼99:1 er) stereoselectivities.