Poly(lactide-co-glycolide)/hydroxyapatite delivery of BMP-2-producing cells: a regional gene therapy approach to bone regeneration

Recombinant human bone morphogenetic protein induces bone formation.

Elizabeth A. Wang, Vicki Rosen, Josephine D’Alessandro et al. · Proceedings of the National Academy of Sciences · 1990 · 1.5K citations · Full text

Medicine, Orthopaedic Surgery, Orthopedic Surgery +13

The Effect of Regional Gene Therapy with Bone Morphogenetic Protein-2-Producing Bone-Marrow Cells on the Repair of Segmental Femoral Defects in Rats*

Jay R. Lieberman, Aaron Daluiski, Sharon Stevenson et al. · Journal of Bone and Joint Surgery · 1999 · 529 citations

Medicine, Orthopaedic Surgery, Surgery +17

Fabrication of biodegradable polymer scaffolds to engineer trabecular bone

Robert C. Thomson, Michael J. Yaszemski, John M. Powers et al. · Journal of Biomaterials Science Polymer Edition · 1996 · 491 citations

Engineering, Bioengineering, Biomedical Engineering +17

Bone Morphogenetic Protein-2

Edward H. Riley, Joseph M. Lane, Marshall R. Urist et al. · Clinical Orthopaedics and Related Research · 1996 · 311 citations

Medicine, Developmental Biology, Orthopaedic Surgery +15

Regional gene therapy with a BMP‐2‐producing murine stromal cell line induces heterotopic and orthotopic bone formation in rodents

Jay R. Lieberman, Lu Q. Le, Lilly Wu et al. · Journal of Orthopaedic Research® · 1998 · 307 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +17