Tissue‐Engineered Cultured Periosteum Used With Platelet‐Rich Plasma and Hydroxyapatite in Treating Human Osseous Defects

Abstract

Compared to PRP with HA, treatment with a combination of HCP sheets, PRP, and HA led to a significantly more favorable clinical improvement in infrabony periodontal defects. A factor likely contributing to these favorable clinical results is the presence of osteogenic cells in the HCP sheets, which provided greater regeneration potential.