Scatchard plot: Common misinterpretation of binding experiments

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

George Scatchard · Annals of the New York Academy of Sciences · 1949 · 19.9K citations

Protein Chemistry, Protein Function, Protein Assembly +5

A graphic method for the determination and presentation of binding parameters in a complex system

Hannah Rosenthal · Analytical Biochemistry · 1967 · 1.5K citations

Engineering, Chemical Analysis, Graphic Method +9

On the Evaluation of the Constants <i> V _m </i> and <i> K _M </i> in Enzyme Reactions

B.H.J. Hofstee · Science · 1952 · 741 citations

Engineering, Biochemistry, Reaction Process +7

Mathematical theory of complex ligand-binding systems at equilibrium: Some methods for parameter fitting

Henry A. Feldman · Analytical Biochemistry · 1972 · 618 citations

Biochemistry, Mathematical Theory, Medicine +10

Properties of graphical representations of multiple classes of binding sites

Irving M. Klotz, Donald L. Hunston · Biochemistry · 1971 · 617 citations

Quantitative Methods, Databases, Media Standards +25