Complex Actions of 2-Aminoethyldiphenyl Borate on Store-operated Calcium Entry

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

Stefan Feske, Yousang Gwack, Murali Prakriya et al. · Nature · 2006 · 2.2K citations

Crac Channel Function, Immunogenetics, Molecular Immunology +10

STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx

Jen Liou, Man Lyang Kim, Won Do Heo et al. · Current Biology · 2005 · 2.1K citations · Full text

Physiology, Ca2+ Sensor Essential

STIM1, an essential and conserved component of store-operated Ca2 <b>+</b> channel function

Jack Roos, Paul J. DiGregorio, Andriy V. Yeromin et al. · The Journal of Cell Biology · 2005 · 1.8K citations · Full text

Depletion of intracellular calcium stores activates a calcium current in mast cells

Markus Hoth, Reinhold Penner · Nature · 1992 · 1.7K citations

Signal Transduction, Molecular Physiology, Cell Signaling +8

STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

Shenyuan L. Zhang, Ying Yu, Jack Roos et al. · Nature · 2005 · 1.4K citations · Full text

Signal Transduction, Molecular Physiology, Ca2+ Sensor +7