Novel cationic pentablock copolymers as non-viral vectors for gene therapy

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.

Otmane Boussif, Frank Lezoualc’h, Maria Antonietta Zanta et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations · Full text

Engineering, In Vivo Gene Therapy, Several Polycations +20

In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis

Dagmar Fischer, Youxin Li, Barbara Ahlemeyer et al. · Biomaterials · 2003 · 2.3K citations

Vitro Cytotoxicity Testing, Engineering, Medicine +9

<i>In Vitro</i> Gene Delivery by Degraded Polyamidoamine Dendrimers

Mary X. Tang, C. T. Redemann, Francis C. Szoka · Bioconjugate Chemistry · 1996 · 799 citations

Structure−Activity Relationships of Water-Soluble Cationic Methacrylate/Methacrylamide Polymers for Nonviral Gene Delivery

Petra van de Wetering, Ed E. Moret, N.M.E. Schuurmans-Nieuwenbroek et al. · Bioconjugate Chemistry · 1999 · 418 citations

Nanomedicine, Engineering, Smart Polymer +15

Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery

Philip R. Dash, Martin L. Read, L B Barrett et al. · Gene Therapy · 1999 · 382 citations

Engineering, Blood Cell, Gene Delivery +6