effects of picotamide on human platelet aggregation, the release reaction and thromboxane B2 production

Malondialdehyde formation as an indicator of prostaglandin production by human platelets.

J B Smith, CM Ingerman, M.J. Silver · PubMed · 1976 · 364 citations

Medicine, Biochemistry, Hematology +16

Thromboxane A2 causes feedback amplification involving extensive thromboxane A2 formation on close contact of human platelets in media with a low concentration of ionized calcium

MA Packham, RL Kinlough-Rathbone, J. F. Mustard · Blood · 1987 · 90 citations · Full text

Medicine, Biochemistry, Hematology +11

Characterization of N,N’-bis(3-Picolyl)-4-Methoxy-Isophtalamide (Picotamide) as a Dual Thromboxane Synthase Inhibitor/Thromboxane A2 Receptor Antagonist in Human Platelets

Paolo Gresele, Hans Deckmyn, Jef Arnout et al. · Thrombosis and Haemostasis · 1989 · 80 citations

Medicine, Medicinal Chemistry, Pharmacology +15

BM 13.177, A SELECTIVE BLOCKER OF PLATELET AND VESSEL WALL THROMBOXANE RECEPTORS, IS ACTIVE IN MAN

Paolo Gresele, Jef Arnout, W. J. Janssens et al. · The Lancet · 1984 · 76 citations

Medicine, Hematology, Pharmacology +14

Familial Bleeding Tendency with Partial Platelet Thromboxane Synthetase Deficiency: Reorientation of Cyclic Endoperoxide Metabolism

G. Defreyn, S.J. Machin, L Carreras et al. · British Journal of Haematology · 1981 · 67 citations

Medicine, Biochemistry, Hematology +17