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Ablation of Very Long Acyl Chain Sphingolipids Causes Hepatic Insulin Resistance in Mice Due to Altered Detergent-Resistant Membranes

DOIFull Paper Access

165

Citations

31

References

2012

Year

Joo‐Won Park, Woo‐Jae Park, Yael Kuperman, Sigalit Boura‐Halfon, Yael Pewzner‐Jung, Anthony H. Futerman
Hepatology

Abstract

We conclude that the sphingolipid acyl chain composition of liver regulates insulin signaling by modifying insulin receptor translocation into membrane microdomains.

References

YearCitations

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