The Human Mismatch Recognition Complex hMSH2-hMSH6 Functions as a Novel Molecular Switch

Distantly related sequences in the alpha‐ and beta‐subunits of ATP synthase, myosin, kinases and other ATP‐requiring enzymes and a common nucleotide binding fold.

John E. Walker, M Saraste, M J Runswick et al. · The EMBO Journal · 1982 · 5.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

Richard Fishel, Mary Kay Lescoe, Manchanahalli R. Satyanarayana Rao et al. · Cell · 1993 · 2.9K citations

Life Sciences, Genetics, Oncology +14

Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer

Christian Bronner, Sean M. Baker, Paul T. Morrison et al. · Nature · 1994 · 2.1K citations

Life Sciences, Genetics, Molecular Genetics +12

Mutations of two P/WS homologues in hereditary nonpolyposis colon cancer

Nicholas C. Nicolaides, Nickolas Papadopoulos, Bo Liu et al. · Nature · 1994 · 1.5K citations

Life Sciences, Genetics, Molecular Genetics +14

Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells

James T. Drummond, Guo‐Min Li, Matthew J. Longley et al. · Science · 1995 · 607 citations

Life Sciences, Genetics, Molecular Biology +15