Concepedia

Human and rat urinary metabolites of the antitumor drug celiptium ® (N2-methyl-9-hydroxyellipticinium acetate, NSC 264137). Identification of cysteine conjugates supporting the “biooxidative alkylation” hypothesis

Bernard Monsarrat, Mohamed Maftouh, Gérard Meunier, Bernard Dugué, Jean Bernadou, Jean‐Pierre Armand, C. Picard-Fraire, Bernard Meunier, Claude Paoletti

Biochemical Pharmacology · 1983 · 24 citations · 4 references

DOI

Concepts

References

4

Bioactivation of the antitumor drugs 9-hydroxyellipticine and derivatives by a peroxidase-hydrogen peroxide system

Christian Auclair, Claude Paoletti · Journal of Medicinal Chemistry · 1981 · 100 citations

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3-(glutathion-S-yl)acetaminophen: a biliary metabolite of acetaminophen.

J. A. Hinson, T J Monks, Mo Hong et al. · Drug Metabolism and Disposition · 1982 · 93 citations

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N-Hydroxyacetaminophen: a postulated toxic metabolite of acetaminophen

Ian C. Calder, S. J. Hart, K. Healey et al. · Journal of Medicinal Chemistry · 1981 · 32 citations

, , +14

Metabolism of the anti-tumour drugs<i>N</i><sup>2</sup>-methyl-9-hydroxyellipticinium acetate (NSC 264137) and<i>N</i><sup>2</sup>-methyl-9-hydroxyolivacinium acetate in the rat: preliminary identification of biliary 9-(<i>O</i>)-glucuronide and 10-(<i>S</i>)-glutathione conjugates

Mohamed Maftouh, Gérard Meunier, Bernard Dugué et al. · Xenobiotica · 1983 · 18 citations