The Journal of Experimental Medicine · 1918 · 24 citations · 0 references
MedicineAnatomyPhysiologyCellular MetabolismHistologyHistopathologyAtmospheric Oxidation ProcessesCellular DegenerationHypoxia AdaptationHypoxia PhysiologyOxygen EffectRabbit PhysiologyCarbon DioxideGlandular HyperplasiaHistology Of Rabbit TissuesHyaline ChangeHyaline DegenerationOxygen Tension EffectsThyroid HyperplasiaTissue Reactions
Exposure of rabbits to an atmosphere of low oxygen content results in a stimulation of the cardiorespiratory systems, in an extension (hyperplasia) of red bone marrow and probably of a thyroid hyperplasia, with the further production of hydropic and hyaline degeneration in the cells of the parenchymatous organs. An atmosphere of high carbon dioxide and normal oxygen content produces, however, a stimulation of the cardiorespiratory systems, but no marrow extension and, in the concentrations used, but slight hydropic degeneration in the parenchyma of the glandular organs.