Concepedia

Progressive Upregulation of PD-1 in Primary and Metastatic Melanomas Associated with Blunted TCR Signaling in Infiltrating T Lymphocytes

Maxime Chapon, Clotilde Randriamampita, E. Maubec, Cécile Badoual, Stéphane Fouquet, Shufang Wang, Eduardo Marinho, David Farhi, Marylène Garcette, S. Jacobelli,

Journal of Investigative Dermatology · 2011 · 86 citations · 23 references

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Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates

Julie R. Brahmer, Charles G. Drake, Ira Wollner et al. · Journal of Clinical Oncology · 2010 · 2.9K citations · Full text

Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes

Mark E. Dudley, John R. Wunderlich, Paul F. Robbins et al. · Science · 2002 · 2.8K citations · Full text

Tumor antigen–specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired

Mojgan Ahmadzadeh, Laura A. Johnson, Bianca Heemskerk et al. · Blood · 2009 · 1.7K citations · Full text

Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma

Andrew T. Parsa, James S. Waldron, Amith Panner et al. · Nature Medicine · 2006 · 1.3K citations

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Tumor B7-H1 Is Associated with Poor Prognosis in Renal Cell Carcinoma Patients with Long-term Follow-up

R. Houston Thompson, Susan M. Kuntz, Bradley C. Leibovich et al. · Cancer Research · 2006 · 863 citations · Full text

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