Cloning of human, mouse and fission yeast recombination genes homologous to RAD51 and recA

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.1K citations · Full text

Dna, Engineering, Dna Analysis +20

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

Andrew P. Feinberg, Bert Vogelstein · Analytical Biochemistry · 1983 · 25.2K citations

Nucleic Acid Chemistry, High Specific Activity, Natural Sciences +6

Rapid and efficient site-specific mutagenesis without phenotypic selection.

Thomas A. Kunkel · Proceedings of the National Academy of Sciences · 1985 · 7.3K citations · Full text

Engineering, Reverse Genetics, Efficient Site-specific Mutagenesis +14

Somatic generation of antibody diversity

Susumu Tonegawa · Nature · 1983 · 3.9K citations

Engineering, Immunology, Synthetic Biology +6

Somatic generation of antibody diversity.

PubMed · 1976 · 3.3K citations