Concepedia

The therapeutic effects of basic fibroblast growth factor contained in gelatin hydrogel microspheres on experimental osteoarthritis in the rabbit knee

Atsuo Inoue, Kenji Takahashi, Yuji Arai, Hitoshi Tonomura, Kei Sakao, Masazumi Saito, Mikihiro Fujioka, Hiroyoshi Fujiwara, Yasuhiko Tabata, Toshikazu Kubo

Arthritis & Rheumatism · 2005 · 101 citations · 33 references

DOI

Abstract

Our findings demonstrated that sustained release of bFGF into the joint had therapeutic effects on OA development in a rabbit model. Our results suggest the potential feasibility of a new conservative treatment for OA.

References

33

THE PREPARATION OF 131I-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY

FC Greenwood, WM Hunter, J. Glover · Biochemical Journal · 1963 · 10.2K citations · Full text

, , +11

Treatment of Deep Cartilage Defects in the Knee with Autologous Chondrocyte Transplantation

Mats Brittberg, Anders Lindahl, Anders Nilsson et al. · New England Journal of Medicine · 1994 · 5.5K citations · Full text

Biochemical and Metabolic Abnormalities in Articular Cartilage from Osteo-Arthritic Human Hips

Henry J. Mankin, HOWARD DORFMAN, Louis Lippiello et al. · Journal of Bone and Joint Surgery · 1971 · 1.9K citations

, , +20

Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis

S.S. Glasson, Roger Askew, Barbara Sheppard et al. · Nature · 2005 · 1.2K citations

, , +6

Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial

Jean‐Yves Reginster, Rita Deroisy, Lucio C. Rovati et al. · The Lancet · 2001 · 1.2K citations

, , +5